Preimplantation Genetic Testing: Between the Private and the Public in the Era of Precision Medicine
DOI:
https://doi.org/10.56294/piii2024277Keywords:
Precision Medicine, Preimplantation Genetic Testing, BioethicsAbstract
This presentation is part of the Strategic Development Project PDE/6 2023-2024 funded by the Secretariat of Science and Technology of the University of Buenos Aires. The project aimed to produce a technical report addressing the scope and limitations of preimplantation genetic testing (PGT) in Argentina. The experiences, progress and findings of our interdisciplinary team comprising researchers from biological sciences and psychology are discussed here.
Two fundamental aspects of the reproductive medicine field were addressed. Firstly, despite the existence of law 26,862/2013 covering assisted reproductive treatments, preimplantation genetic tests remain excluded from the Mandatory Medical Plan, highlighting access limitations. Moreover, challenges arise from the lack of specific regulations on central issues for the development of reproductive treatments, such as the legal status of non-implanted embryos. This particular situation prompted an analysis of the paradigm shift from collective health to precision medicine.
Within this framework, our work critically examined the implications of PGT on approaches to knowledge and interventions in living organisms. We explored how PGT shapes notions of uncertainty, control, anticipation and the individualization of pathological conditions, shedding light on evolving forms of subjectivity. Additionally, we scrutinized genetic essentialism and determinism as discourses that either flatten differences or advocate for the "optimization" of life itself
References
Cortés MF. Medicina de precisión de enfermedades raras. Revista Médica Clínica Las Condes. 2022;33(2):148-153. doi: 10.1016/j.rmclc.2022.03.005.
Catoggio MS, Irrazábal G. Genética, derechos humanos y política estatal en la Argentina: la creación del Banco Nacional de Datos Genéticos y del Registro Nacional de Datos Genéticos vinculados a delitos sexuales (1987-2017). Vía Iuris. 2020;(29):1–52. doi: 10.37511/viaiuris.n29a5.
Luna F, Salles ALF, Costa MV, Sommer SE, Vidiella G. Bioética: nuevas reflexiones sobre debates clásicos. Buenos Aires: Fondo de Cultura Económica; 2008.
Sommer SE. Estado actual de los test genéticos en países en desarrollo: el caso de América Latina y en especial Argentina. Revista QuímicaViva. 2008;7(3):186-196.
Ariza L. Ética en vivo: Sobre el trabajo ético en el diagnóstico genético premplantatorio (PGD) en Argentina. Política Soc. 2019;56(3):669-690. doi: 10.5209/poso.59906.
Lima NS, Iturburu MR, Martínez AG. Repensando la autonomía y la responsabilidad en el contexto de las terapias de ingeniería genética en el contexto latinoamericano. HOLOS. 2022;3:1-26. doi: 10.15628/holos.2022.13387.
Zegers-Hochschild F, Crosby JA, Musri C, Souza MDCBD, Martínez AG, Silva AA, et al. Celebrating 30 years of ART in Latin America; and the 2018 report. JBRA Assisted Reproduction. 2021;25(4):617-639. doi: 10.5935/1518-0557.20210055.
Álvarez Sedó C. Estudio genético pre-implantatorio para aneuploidías (PGT-A): una revisión crítica actualizada. Re- producción. 2018;33(1):21-43.
Coco R, Coco F, Mincman J, Mondadori A, Mendonza GM, Santomé M, et al. Experiencia argentina de diagnóstico genético preimplantatorio (PGD) con biopsia de Trofoblasto. Revista Bioquímica y Patología Clínica. 2018;82(1):34-44.
Gigerenzer G, Gaissmaier W, Kurz-Milcke E, Schwartz LM, Woloshin S. Helping doctors and patients make sense of health statistics. Psychological Science in the Public Interest. 2007;8(2):53-96. doi: 10.1111/j.1539-6053.2008.00033.x.
WHO Expert Committee on Human Genetics, Organization WH. Genetic counselling: third report of the WHO Expert Committee on Human Genetics [Internet]. World Health Or- ganization; 1969 [citado 27 abr 2023]. Disponible en: https:// tinyurl.com/2t2yubze.
Paim JS, Almeida Filho N. La crisis de la salud pública y el movimiento de la salud colectiva en Latinoamérica. Cuadernos Médico Sociales. 1999;75:5-30.
Dussel ED. 14 tesis de ética: hacia la esencia del pensamiento crítico. Madrid: Editorial Trotta; 2016.
Lima, Natacha Salomé et al. “From collective health to "personalized" medicine: bioethical challenges in preimplantation genetic testing from a North-South perspective.” “De la salud colectiva a la medicina “personalizada”: desafíos bioéticos de la evaluación genética preimplantatoria desde la perspectiva norte-sur.” Salud colectiva vol. 19 e4481. 12 Sep. 2023, doi:10.18294/sc.2023.4481
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Copyright (c) 2024 Natacha Salomé Lima, Miguel Adrián Romero, Ailin Delvitto, Ana Tropea, María Alejandra Petino Zappala, Nahuel Pallitto, Fernando Pérez Ferretti, María Paula Paragis (Author)
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