Argentina: a meta-analysis of the research agenda in cancer and socio-environmental health

Authors

  • Emiliano Ariel Martínez Viademonte Instituto de Biociencias, Biotecnología y Biología Traslacional (iB3), Departamento de Fisiología, Biología Molecular y Celular (DFBMC), Facultad de Ciencias Exactas y Naturales (FCEyN), Universidad de Buenos Aires (UBA), Buenos Aires, Argentina. Author https://orcid.org/0009-0006-3446-1237
  • Mercedes García Carrillo Instituto de Biociencias, Biotecnología y Biología Traslacional (iB3), Departamento de Fisiología, Biología Molecular y Celular (DFBMC), Facultad de Ciencias Exactas y Naturales (FCEyN), Universidad de Buenos Aires (UBA), Buenos Aires, Argentina. Author https://orcid.org/0000-0001-7868-6047
  • Matías Blaustein Instituto de Biociencias, Biotecnología y Biología Traslacional (iB3), Departamento de Fisiología, Biología Molecular y Celular (DFBMC), Facultad de Ciencias Exactas y Naturales (FCEyN), Universidad de Buenos Aires (UBA), Buenos Aires, Argentina. Author https://orcid.org/0000-0001-6309-6888

DOI:

https://doi.org/10.56294/piii2024296

Keywords:

Research agenda, Cancer, Argentina, Socio-environmental health, Conflict of Interest

Abstract

The economic agenda and corporate interests can influence and/or drive the public biomedical research agenda, establishing priorities in the study topics. In this work, we analyzed the contents of the cancer research agenda in Argentina, including a comprehensive analysis of the different epistemological dimensions associated with the study of this set of pathologies.
Methods: A bibliometric analysis was conducted based on 7319 scientific articles published between 1980 and 2023, divided into two periods (1980-2000 and 2001-2023), containing one or more authors with Argentina as their affiliation country. The PubMed database and the CorText platform were used to work with the database and to extract the most frequent multi-terms. Through this extraction, the main categories linked to cancer research, their preponderance in the local research agenda, and the place occupied by approaches linked to the molecular, social, and environmental determinants of cancer could be visualized. The content of this cancer research agenda was represented through co-occurrence networks of the predominant multi-terms found in the articles' titles, keywords, and abstracts.
Results: The results reflected a strong predominance of methodological approaches associated with molecular and cellular biology. In addition, terms associated with breast cancer had a strong predominance in recent years. The analysis also revealed that the study of socio-environmental factors influencing the development and progression of diseases such as occupational, environmental, and exposure to xenobiotics remained marginal in the cancer research agenda of Argentina during the last four decades.
Conclusions: It is concluded that the orientation of the Argentine cancer research agenda excludes, with few exceptions, the prevention and study of socio-environmental factors associated with the development and progression of cancer, favoring a reductionist methodological approach anchored in Molecular and Cellular Biology and linked to the development of therapeutic and pharmacological interventions

References

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Testoni, F. E., García Carrillo, M., Gagnon, M. A., Rikap, C., & Blaustein, M. (2021). Whose shoulders is health research standing on? Determining the key actors and contents of the prevailing biomedical research agenda. PLoS One, 16(4), e0249661.

García Carrillo, M., Testoni, F., Gagnon, M. A., Rikap, C., & Blaustein, M. (2022). Academic dependency: the influence of the prevailing international biomedical research agenda on Argentina’s CONICET. Heliyon, 8(11).

Gárgano, C. (2023). Agroextractivism in Argentina environmental health, scientific agendas, and socioecological crisis. Frontiers in Public Health, 11, 1304514.

García Carrillo, M., Gagnon, M. A., & Blaustein, M. (2024). Current priorities in health research agendas: tensions between public and commercial interests in prioritizing biomedical, social, and environmental aspects of health. Frontiers in Medicine, 11, 1391982.

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Published

2024-05-08

How to Cite

1.
Martínez Viademonte EA, García Carrillo M, Blaustein M. Argentina: a meta-analysis of the research agenda in cancer and socio-environmental health. SCT Proceedings in Interdisciplinary Insights and Innovations [Internet]. 2024 May 8 [cited 2024 Sep. 19];2:296. Available from: https://proceedings.ageditor.ar/index.php/piii/article/view/265