Aortic aneurysm - endovascular repair vs open surgery: systematic literature review
DOI:
https://doi.org/10.56294/piii2024330Keywords:
Abdominal aortic aneurysm, Endovascular repair, Open abdominal surgery, Complications, ReinterventionsAbstract
Background: Abdominal aortic aneurysm is a pathology with a prevalence in men over 65 years of age of more than 8% worldwide. It has a high mortality and morbidity rate, representing between 1 and 2% of deaths. When surgical repair is indicated there are two options, endovascular repair and open abdominal surgery. Endovascular repair in elective patients seems to be the best option as it is a less invasive method, although so far there is no conclusive evidence on the advantages in certain subgroups. On the other hand, open surgery, taking into account the anatomy, age and context of the patient, could be more beneficial in certain groups. In conclusion, the choice of the therapeutic method in an elective situation will depend on the individual context of each patient, considering the possible complications and reinterventions that may affect the quality of life and put the patient's life at risk.
Material and methods: An in-depth literature search will be performed in the PubMed database, using inclusion and exclusion criteria, and filters in the last ten years where randomized clinical trial studies, case-control studies and systematic reviews will be evaluated. Always using the following search terms: "abdominal aortic aneurysm", "endovascular repair" and "open abdominal surgery".
Results: Six studies were selected after applying the inclusion and exclusion criteria. The articles compared and analyzed the use of endovascular repair (EVAR) and open surgical repair (OSR). Both methods were evaluated and compared using the variables of short- and long-term complications and the rate of reinterventions. It was found that patients who received EVAR had a higher rate of total complications with a high predominance after 4 years post intervention. As for reinterventions, there was a significantly higher rate in those who received EVAR with respect to those who underwent OSR.
Conclusion: Endovascular repair showed a higher rate of reinterventions than open surgery. As well as a greater number of long-term complications. These are results that should be taken into account when evaluating it as a therapeutic option, especially in certain groups of patients. Thus, open surgery appears to be a safer treatment. Especially in the long term and in groups of young patients without comorbidities
References
Torres-Fonseca M, Galan M, Martinez-Lopez D, Cañes L, Roldan-Montero R, Alonso J, et al. Pathophisiology of abdominal aortic aneurysm: biomarkers and novel therapeutic targets. Clin E Investig En Arterioscler Publicacion Of Soc Espanola Arterioscler;31(4):166-77.
Nordon IM, Hinchliffe RJ, Loftus IM, Thompson MM. Pathophysiology and epidemiology of abdominal aortic aneurysms. Nat Rev Cardiol. febrero de 2011;8(2):92102.
Forsdahl SH, Singh K, Solberg S, Jacobsen BK. Risk factors for abdominal aortic aneurysms: a 7-year prospective study: the Tromsø Study, 1994-2001. Circulation. 28 de abril de 2009;119(16):2202-8.
Earnshaw JJ, Shaw E, Whyman MR, Poskitt KR, Heather BP. Screening for abdominal aortic aneurysms in men.
BMJ. 8 de mayo de 2004;328(7448):1122-4.
Sandford RM, Bown MJ, London NJ, Sayers RD. The Genetic Basis of Abdominal Aortic Aneurysms: A Review. Eur J Vasc Endovasc Surg. 1 de abril de 2007;33(4):38190.
Michel JB, Martin-Ventura JL, Egido J, Sakalihasan N, Treska V, Lindholt J, et al. Novel aspects of the pathogenesis of aneurysms of the abdominal aorta in humans. Cardiovasc Res. 1 de abril de 2011;90(1):18-27.
Sweeting MJ, Masconi KL, Jones E, Ulug P, Glover MJ, Michaels JA, et al. Analysis of clinical benefit, harms, and cost-effectiveness of screening women for abdominal aortic aneurysm. The Lancet. 11 de agosto de 2018;392(10146):487-95.
Haque K, Bhargava P. Abdominal Aortic Aneurysm. Am Fam Physician. agosto de 2022;106(2):165-72.
Townsend CM, Beauchamp RD, Evers BM, Mattox KL. Sabiston. Tratado de cirugía: Fundamentos biológicos de la práctica quirúrgica moderna. Elsevier Health Sciences; 2017. 2168 p.
Jameson JL. Harrison principios de medicina interna. McGraw-Hill; 2018. 1647 p.
Sweeting MJ, Thompson SG, Brown LC, Powell JT, on behalf of the RESCAN collaborators. Meta-analysis of individual patient data to examine factors affecting growth and rupture of small abdominal aortic aneurysms. Br J Surg. 1 de mayo de 2012;99(5):655-65.
Endovascular versus Open Repair of Abdominal Aortic Aneurysm. N Engl J Med. 20 de mayo de;362(20):1863-71.
Lederle FA, Kyriakides TC, Stroupe KT, Freischlag JA, Padberg FT, Matsumura JS, et al. Open versus Endovascular Repair of Abdominal Aortic Aneurysm. N Engl J Med. 30 de mayo de 2019;380(22):2126-35.
Han Y, Zhang S, Zhang J, Ji C, Eckstein HH. Outcomes of Endovascular Abdominal Aortic Aneurysm Repair in Octogenarians: Meta-analysis and Systematic Review. Eur J Vasc Endovasc Surg. octubre de 2017;54(4):454-63.
Lederle FA, Freischlag JA, Kyriakides TC, Matsumura JS, Padberg FT, Kohler TR, et al. Long-Term Comparison of Endovascular and Open Repair of Abdominal Aortic Aneurysm. N Engl J Med. 22 de noviembre de 2012;367(21):1988-97.
Endovascular aneurysm repair versus open repair in patients with abdominal aortic aneurysm (EVAR trial 1): randomised controlled trial. The Lancet. junio de 2005;365(9478):2179-86.
Becquemin JP, Pillet JC, Lescalie F, Sapoval M, Goueffic Y, Lermusiaux P, et al. A randomized controlled trial of endovascular aneurysm repair versus open surgery for abdominal aortic aneurysms in low- to moderate-risk patients. Journal of Vascular Surgery. mayo de 2011;53(5):1167-1173.e1.
Van Schaik TG, Yeung KK, Verhagen HJ, De Bruin JL, Van Sambeek MRHM, Balm R, et al. Long-term survival and secondary procedures after open or endovascular repair of abdominal aortic aneurysms. Journal of Vascular Surgery. noviembre de 2017;66(5):1379-89.
De Bruin JL, Karthikesalingam A, Holt PJ, Prinssen M, Thompson MM, Blankensteijn JD, et al. Predicting reinterventions after open and endovascular aneurysm repair using the St George’s Vascular Institute score. Journal of Vascular Surgery. junio de 2016;63(6):1428-e1.
Downloads
Published
Issue
Section
License
Copyright (c) 2024 Jano Matias Legaz, Norberto Blanco (Author)
This work is licensed under a Creative Commons Attribution 4.0 International License.
The article is distributed under the Creative Commons Attribution 4.0 License. Unless otherwise stated, associated published material is distributed under the same licence.