Risk factors for nosocomial candiduria in patients with bladder catheterization, diagnosis and treatment
DOI:
https://doi.org/10.56294/piii2024337Keywords:
Nosocomial Candiduria, Candida Species, Candidiasis, Urinary Catherter, Diagnosis, Risk Factor’sAbstract
Introduction: nosocomial candiduria is defined as the detection of Candida spp. in the urine of hospitalized patients who have a bladder catheter.
Objectives: to analyze risk factors in patients with nosocomial candiduria.
Methods: a literature review was carried out in PubMed, Google Academic and SciELO databases. Inclusion criteria were used, and search terms related to “Candiduria”, “Candidiasis”, “risk factors” and “urinary tract infections” were used to retrieve the records.
Results: of the 92 articles identified, 19 were selected for a comprehensive analysis. The main risk factors associated with nosocomial candiduria in patients with bladder catheters included prolonged use of urinary catheters, hospitalization in intensive care units (ICU), immunosuppression, diabetes mellitus, advanced age and the use of broad-spectrum antibiotics. The most frequently involved species were Candida albicans (65,22 %) and Candida glabrata (20-30 %), highlighting antifungal resistance in some of these species.
Conclusions: the prolonged use of bladder catheters, together with hospitalization in the ICU, are the main risk factors for the development of nosocomial candiduria. In addition, immunosuppression, diabetes and prolonged use of antibiotics play an important role in the development of this infection. The implementation of protocols that include the rational use of antibiotics, the monitoring of patients at risk and the improvement of urological procedures is key to reduce the incidence and improve the management of candiduria
References
1. Cornistein W, Cremona A, Chattas AL, Luciani A, Daciuk L, Juárez PA, et al. Infección del tracto urinario asociada a sonda vesical: Actualización y recomendaciones intersociedades. Med B Aires. agosto de 2018;78(4):258-64.
2. Jiménez-Guerra G, Moreno-Torres IC, Gutiérrez-Soto M, Vazquez-Alonso F, Sorlózano-Puerto A, Navarro-Marí JM, et al. Candiduria en pacientes hospitalizados: etiología, sensibilidad a los fármacos antifúngicos y factores de riesgo. Rev Esp Quimioter. agosto de 2018;31(4):323-8.
3. Gharaghani M, Taghipour S, Halvaeezadeh M, Mahmoudabadi AZ. Candiduria; a review article with specific data from Iran. Turk J Urol. noviembre de 2018;44(6):445.
4. Rihova ZJ, Slobodova L, Hrabovska A. Micafungin Is an Efficient Treatment of Multi Drug-Resistant Candida glabrata Urosepsis: A Case Report. J Fungi [Internet]. octubre de 2021 [citado 21 de noviembre de 2023];7(10). Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538929/
5. Thomas-Rüddel DO, Schlattmann P, Pletz M, Kurzai O, Bloos F. Risk Factors for Invasive Candida Infection in Critically Ill Patients: A Systematic Review and Meta-analysis. Chest. febrero de 2022;161(2):345-55.
6. Infecciones de la Vías Urinarias y de Trasmisión Sexual | Nefrología al día [Internet]. [citado 21 de noviembre de 2023]. Disponible en: http://www.nefrologiaaldia.org/es-articulo-infecciones-vias-urinarias-trasmision-sexual-462
7. He Z, Liu Y, Wang T, Cheng Y, Chen J, Wang F. Candiduria in hospitalized patients: an investigation with the Sysmex UF-1000i urine analyzer. PeerJ. 20 de mayo de 2019;7:e6935.
8. Almeida VF de, Quiliici MCB, Sabino SS, Resende DS, Rossi I, Campos PA de, et al. Appraising epidemiology data and antimicrobial resistance of urinary tract infections in critically ill adult patients: a 7-year retrospective study in a referral Brazilian hospital. São Paulo Med J [Internet]. 2023 [citado 21 de noviembre de 2023];141(6). Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10181834/
9. E H, M N, M A, Cm C, Dm J. A systematic review of the impact of antifungal stewardship interventions in the United States. Ann Clin Microbiol Antimicrob [Internet]. 21 de agosto de 2019 [citado 21 de noviembre de 2023];18(1). Disponible en: https://pubmed.ncbi.nlm.nih.gov/31434563/
10. Radesca Moncayo Y. Vaginal candidiasis, predisposing factors, symptoms and treatment. SCT Proceedings in Interdisciplinary Insights and Innovations. 2024; 2:347. https://doi.org/10.56294/piii2024347
11. Peláez Yáñez LA, Orraca Castillo O, Solana Rodríguez JO, García García M, Hernández Pacheco JI. Clinical diagnosis of chronic mucocutaneous candidiasis in a patient with recurrent staphylococcal infections. Multidisciplinar (Montevideo). 2024; 2:63. https://doi.org/10.62486/agmu202463
Downloads
Published
Issue
Section
License
Copyright (c) 2024 Maita Itanare, Yohismari Del Valle, Virginia Marta Jewtuchowicz (Author)
This work is licensed under a Creative Commons Attribution 4.0 International License.
The article is distributed under the Creative Commons Attribution 4.0 License. Unless otherwise stated, associated published material is distributed under the same licence.