Pharmacological and non-pharmacological management of Polycystic Ovary Syndrome: a systematic review

Abstract

Background: Polycystic ovarian syndrome (PCOS) is a common endocrine disorder characterized by menstrual irregularities and elevated serum androgen levels, accompanied by insulin resistance. This review emphasizes the importance of knowledge of health professionals about lifestyle interventions and weight loss as a form of non-pharmacological treatment, appropriate clinical management, and the pharmacological options available according to the profile. of each patient.  Objective: - Integrate, analyze, identify and manage through the signs and symptoms the key options for the management of the treatment in an individualized way of the polycystic ovary syndrome based on the available scientific publications. Material and Methods: Data collection was carried out through a search in online databases: PUBMED. The articles were downloaded from the cited platforms, and Zotero was used to make the proper citations and references. The research will be made up of published and updated literature that reflects the importance of knowledge about the pharmacological and non-pharmacological management of polycystic ovary syndrome. Results and Discursion: Thirteen studies that met the criteria that were related to the object of study were included. According to the results achieved the study allowed obtaining a more detailed view of studies that emerged from the data search, highlighting categories a such as those that reflect the importance of pharmacological and no pharmacological treatment of PCOS, individualized treatment management for each patient focusing on the improvement of the symptoms generated by the syndrome and avoiding possible complications such as infertility. Conclusion: Treatment for polycystic ovary syndrome consist lifestyle changes, such as weight reduction, especially in obese women, physical exercise, and pharmacotherapy, which is a supportive measure to improve results. Abbreviations: (A4) Androstenediones, (DHEA) Dehydroepiandrosterone, (FAI) Androgens free (FT) Free testosterone, (IGT) Glucose intolerance, (LH): Luteinizing hormone, (PCOS) Polycystic ovary syndrome, (SHBG) Sex hormone binding globulin, (TT) Total testosterone